Hepatitis Monthly

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Prevalence Rate of Hepatitis B Virus in Pregnancy: Implications From a Systematic Review and Meta-Analysis of Studies Published From 2000 to 2016

Masoud Behzadifar 1 , Nicola Luigi Bragazzi 2 , Rabeh Movagharnia 3 , Haniye Sadat Sajadi 4 , Sanaz Heidarvand Ghelichi 5 , Morteza Salemi 6 , Rahim Sohrabi 7 , Roghayeh Mohammadibakhsh 8 , Masood Taheri Mirghaed 8 , Meysam Behzadifar 9 , Ahmad Ghashghaee 10 , Wesam Kooti 11 , Mariano Martini 12 , Maryam Darvishnia 13 , Maryam Saran 9 and Seyed Moayed Alavian 14 , *
Authors Information
1 Hepatitis Research Center, Lorestan University of Medical Sciences, Khorramabad, IR Iran
2 Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy
3 Microbiology Department, Azad University of Varamin -Pishva, Tehran, IR Iran
4 National Institute of Health Research, Tehran University of Medical Sciences, Tehran, IR Iran
5 Bahrami Pediatric Hospital, Tehran University of Medical Sciences, Tehran, IR Iran
6 Social Determinants in Health Promotion Research Center, Hormozgan Health Institute, Hormozgan University of Medical Sciences, Bandar Abbas, IR Iran
7 Iranian Social Security Organization, Zanjan Province Health Administration, Zanjan, IR Iran
8 Department of Health Services Management, School of Health Management and Information Sciences, Iran University of Medical Sciences, Tehran, IR Iran
9 Social Determinants of Health Research Center, Lorestan University of Medical Sciences, Khorramabad, IR Iran
10 Student Research Committee, Department of Health Services Management Branch, School of Health Management and Information Sciences, Iran University of Medical Sciences, Tehran, IR Iran
11 Student Research Committee, Kurdistan University of Medical Sciences, Sanandaj, IR Iran
12 Section of History of Medicine and Ethics, Department of Health Sciences (DISSAL), University of Genoa, Genoa
13 Department of Nursing, Islamic Azad University Khorramabad Branch, Khorramabad, IR Iran
14 Research Center for Gastroenterology and Liver Diseases (BRCGL), Baqiyatallah University of Medical Sciences, Tehran, IR Iran
Article information
  • Hepatitis Monthly: January 2018, 18 (1); e14574
  • Published Online: January 15, 2018
  • Article Type: Review Article
  • Received: June 6, 2017
  • Revised: November 11, 2017
  • Accepted: December 27, 2017
  • DOI: 10.5812/hepatmon.14574

To Cite: Behzadifar M, Luigi Bragazzi N, Movagharnia R, Sajadi H S, Heidarvand Ghelichi S, et al. Prevalence Rate of Hepatitis B Virus in Pregnancy: Implications From a Systematic Review and Meta-Analysis of Studies Published From 2000 to 2016, Hepat Mon. 2018 ; 18(1):e14574. doi: 10.5812/hepatmon.14574.

Copyright © 2018, Hepatitis Monthly. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Methods
3. Results
4. Discussion
  • 1. World Health Organization (WHO). World Health Organization, (WHO), hepatitis B,Fact sheet 2016. Geneva, Switzerland: World Health Organization; 2016. Available from: http://www.who.int/mediacentre/factsheets/fs204/en/.
  • 2. Salehi Vaziri M, Sadeghi F, Almasi Hashiani A, Gholami Fesharaki M, Alavian SM. Hepatitis B virus infection in the general population of iran, an updated systematic review and meta analysis. Hepat Mon. 2016;16(4):35577. doi: 10.5812/hepatmon.35577. [PubMed: 27257428].
  • 3. Babanejad M, Izadi N, Najafi F, Alavian SM. The HBsAg prevalence among blood donors from eastern mediterranean and middle eastern countries, a systematic review and meta analysis. Hepat Mon. 2016;16(3):35664. doi: 10.5812/hepatmon.35664. [PubMed: 27226804].
  • 4. Zampino R, Sagnelli C, Boemio A, Sagnelli E, Coppola N. Treatment of chronic HBV infection in developing countries. Ann Hepatol. 2016;15(6):816-23. doi: 10.5604/16652681.1222096. [PubMed: 27740514].
  • 5. Chan SL, Wong VW, Qin S, Chan HL. Infection and Cancer: The Case of Hepatitis B. J Clin Oncol. 2016;34(1):83-90. doi: 10.1200/JCO.2015.61.5724. [PubMed: 26578611].
  • 6. Rukunuzzaman M, Afroza A. Risk factors of hepatitis B virus infection in children. Mymensingh Med J. 2011;20(4):700-8. [PubMed: 22081192].
  • 7. Kabir A, Alavian SM, Ahanchi N, Malekzadeh R. Combined passive and active immunoprophylaxis for preventing perinatal transmission of the hepatitis B virus in infants born to HBsAg positive mothers in comparison with vaccine alone. Hepatol Res. 2006;36(4):265-71. doi: 10.1016/j.hepres.2006.08.001. [PubMed: 16965939].
  • 8. Gentile I, Borgia G. Vertical transmission of hepatitis B virus: challenges and solutions. Int J Womens Health. 2014;6:605-11. doi: 10.2147/IJWH.S51138. [PubMed: 24966696].
  • 9. Nelson NP, Easterbrook PJ, McMahon BJ. Epidemiology of hepatitis B virus infection and impact of vaccination on disease. Clin Liver Dis. 2016;20(4):607-28. doi: 10.1016/j.cld.2016.06.006. [PubMed: 27742003].
  • 10. World Health Organization (WHO). Global health sector strategy on viral hepatitis 2016-2021. Geneva, Switzerland: World Health Organization; 2016. Available from: http://www.who.int/hepatitis/strategy2016-2021/ghss-hep/en/.
  • 11. Stang A. Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. Eur J Epidemiol. 2010;25(9):603-5. doi: 10.1007/s10654-010-9491-z. [PubMed: 20652370].
  • 12. Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gotzsche PC, Ioannidis JP, et al. The PRISMA statement for reporting systematic reviews and meta analyses of studies that evaluate healthcare interventions, explanation and elaboration. BMJ. 2009;339:2700. doi: 10.1136/bmj.b2700. [PubMed: 19622552].
  • 13. Behzadifar M BMSHTMMFZMBR. Prevalence of hepatitis B in pregnancy: a systematic review and meta-analysis. University of York, UK: PROSPERO International prospective register of systematic reviews, CRD42016041985; 2016. Available from: www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42016041985..
  • 14. DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials. 1986;7(3):177-88. [PubMed: 3802833].
  • 15. DerSimonian R. Combining evidence from clinical trials. Anesth Analg. 1990;70(5):475-6. [PubMed: 2139548].
  • 16. Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ. 2003;327(7414):557-60. doi: 10.1136/bmj.327.7414.557. [PubMed: 12958120].
  • 17. Baker WL, White CM, Cappelleri JC, Kluger J, Coleman CI, Health Outcomes P, et al. Understanding heterogeneity in meta analysis: the role of meta regression. Int J Clin Pract. 2009;63(10):1426-34. doi: 10.1111/j.1742-1241.2009.02168.x. [PubMed: 19769699].
  • 18. Thabane L, Mbuagbaw L, Zhang S, Samaan Z, Marcucci M, Ye C, et al. A tutorial on sensitivity analyses in clinical trials: the what, why, when and how. BMC Med Res Methodol. 2013;13:92. doi: 10.1186/1471-2288-13-92. [PubMed: 23855337].
  • 19. Leimu R, Koricheva J. Cumulative meta-analysis: a new tool for detection of temporal trends and publication bias in ecology. Proc Biol Sci. 2004;271(1551):1961-6. doi: 10.1098/rspb.2004.2828. [PubMed: 15347521].
  • 20. Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997;315(7109):629-34. [PubMed: 9310563].
  • 21. Jonas MM. Hepatitis B and pregnancy: an underestimated issue. Liver Int. 2009;29 Suppl 1:133-9. doi: 10.1111/j.1478-3231.2008.01933.x. [PubMed: 19207977].
  • 22. Pawlowska M, Pniewska A, Pilarczyk M, Kozielewicz D, Domagalski K. Prophylaxis of vertical HBV infection. Expert Opin Drug Saf. 2016;15(10):1361-8. doi: 10.1080/14740338.2016.1211106. [PubMed: 27402246].
  • 23. Visvanathan K, Dusheiko G, Giles M, Wong ML, Phung N, Walker S, et al. Managing HBV in pregnancy. Prevention, prophylaxis, treatment and follow-up: position paper produced by Australian, UK and New Zealand key opinion leaders. Gut. 2016;65(2):340-50. doi: 10.1136/gutjnl-2015-310317. [PubMed: 26475631].
  • 24. Filippelli M, Lionetti E, Pulvirenti A, Gennaro A, Lanzafame A, Marseglia GL, et al. New approaches in hepatitis B vaccination for celiac disease. Immunotherapy. 2014;6(8):945-52. doi: 10.2217/imt.14.64. [PubMed: 25313572].
  • 25. Filippelli M, Lionetti E, Gennaro A, Lanzafame A, Arrigo T, Salpietro C, et al. Hepatitis B vaccine by intradermal route in non responder patients: an update. World J Gastroenterol. 2014;20(30):10383-94. doi: 10.3748/wjg.v20.i30.10383. [PubMed: 25132754].
  • 26. Bonanni P. Universal hepatitis B immunization, infant, and infant plus adolescent immunization. Vaccine. 1998;16 Suppl:17-22. [PubMed: 9915027].
  • 27. Kalantari H, Davari M, Akbari M, Hejazi SM, Kalantari M, Zakerin S, et al. The estimation of direct medical costs of treating patients with chronic hepatitis B and C in iran. Int J Prev Med. 2012;3(3):191-6. [PubMed: 22448312].
  • 28. Lu J, Xu A, Wang J, Zhang L, Song L, Li R, et al. Direct economic burden of hepatitis B virus related diseases: evidence from Shandong, China. BMC Health Serv Res. 2013;13:37. doi: 10.1186/1472-6963-13-37. [PubMed: 23368750].
  • 29. G. B. D. Mortality , Causes of Death C. Global, regional, and national age sex specific all cause and cause specific mortality for 240 causes of death, 1990-2013, a systematic analysis for the global burden of disease study 2013. Lancet. 2015;385(9963):117-71. doi: 10.1016/S0140-6736(14)61682-2. [PubMed: 25530442].
  • 30. Brown RJ, McMahon BJ, Lok AS, Wong JB, Ahmed AT, Mouchli MA, et al. Antiviral therapy in chronic hepatitis B viral infection during pregnancy: A systematic review and meta-analysis. Hepatology. 2016;63(1):319-33. doi: 10.1002/hep.28302. [PubMed: 26565396].
  • 31. United Nations Development Programme (UNDP). Human development report 2010, the real wealth of nations, pathways to human development. New York, United States: United Nations Development Programme, (UNDP); 2013, [cited 23 Sep]. Available from: http://hdr.undp.org/en/reports/global/hdr2010/.
  • 32. Lee KS, Park SC, Khoshnood B, Hsieh HL, Mittendorf R. Human development index as a predictor of infant and maternal mortality rates. J Pediatr. 1997;131(3):430-3. [PubMed: 9329421].
  • 33. Wang AL, Qiao YP, Wang LH, Fang LW, Wang F, Jin X, et al. Integrated prevention of mother-to-child transmission for human immunodeficiency virus, syphilis and hepatitis B virus in China. Bull World Health Organ. 2015;93(1):52-6. doi: 10.2471/BLT.14.139626. [PubMed: 25558108].
  • 34. Chen L, Evans T, Anand S, Boufford JI, Brown H, Chowdhury M, et al. Human resources for health: overcoming the crisis. Lancet. 2004;364(9449):1984-90. doi: 10.1016/S0140-6736(04)17482-5. [PubMed: 15567015].
  • 35. Anand S, Barnighausen T. Human resources and health outcomes: cross-country econometric study. Lancet. 2004;364(9445):1603-9. doi: 10.1016/S0140-6736(04)17313-3. [PubMed: 15519630].

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