Hepatitis Monthly

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The Hepatitis B Vaccine and Celiac Disease: More Lights Than Shadows?

Giovanna Vitaliti 1 , * , Angela Lanzafame 1 , Mario La Rosa 1 and Salvatore Leonardi 1
Authors Information
1 Department of Pediatrics, University of Catania, Catania, Italy
Article information
  • Hepatitis Monthly: January 01, 2013, 13 (1); e7878
  • Published Online: January 20, 2013
  • Article Type: Letter
  • Received: August 23, 2012
  • Accepted: September 24, 2012
  • DOI: 10.5812/hepatmon.7878

To Cite: Vitaliti G, Lanzafame A, La Rosa M, Leonardi S. The Hepatitis B Vaccine and Celiac Disease: More Lights Than Shadows?, Hepat Mon. 2013 ; 13(1):e7878. doi: 10.5812/hepatmon.7878.

Copyright © 2013, Kowsar Corp. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
  • 1. Noh KW, Poland GA, Murray JA. Hepatitis B vaccine nonresponse and celiac disease. Am J Gastroenterol. 2003; 98(10): 2289-92[DOI][PubMed]
  • 2. Nemes E, Lefler E, Szegedi L, Kapitany A, Kovacs JB, Balogh M, et al. Gluten intake interferes with the humoral immune response to recombinant hepatitis B vaccine in patients with celiac disease. Pediatrics. 2008; 121(6)-6
  • 3. Leonardi S, La Rosa M. Are hepatitis B virus and celiac disease linked? Hepat Mon. 2010; 10(3): 173-5[PubMed]
  • 4. Leonardi S, Del Giudice MM, Spicuzza L, Spina M, La Rosa M. Hepatitis B vaccine administered by intradermal route in patients with celiac disease unresponsive to the intramuscular vaccination schedule: a pilot study. Am J Gastroenterol. 2010; 105(9): 2117-9[DOI][PubMed]
  • 5. Dubois B, Bridon JM, Fayette J, Barthelemy C, Banchereau J, Caux C, et al. Dendritic cells directly modulate B cell growth and differentiation. J Leukoc Biol. 1999; 66(2): 224-30[PubMed]
  • 6. Leonardi S, Pratico AD, Lionetti E, Spina M, Vitaliti G, Rosa ML. Intramuscular vs intradermal route for hepatitis B booster vaccine in celiac children. World J Gastroenterol. 2012; 18(40): 5729-33[DOI][PubMed]
  • 7. Sangfelt P, Uhnoo I, Reichard O, Weiland O. A low-dose intradermal hepatitis B vaccine programme in health-care workers and students is highly effective and cost saving: a retrospective follow-up survey in the clinical setting. Scand J Gastroenterol. 2008; 43(4): 465-72[DOI][PubMed]
  • 8. Leonardi S, Leggio T, Sciacca A, Di Gregorio F, Musumeci S. Intradermal hepatitis B vaccination in thalassaemia. Arch Dis Child. 1990; 65(5): 527-9[DOI][PubMed]
  • 9. Zanetti AR, Mariano A, Romano L, D'Amelio R, Chironna M, Coppola RC, et al. Long-term immunogenicity of hepatitis B vaccination and policy for booster: an Italian multicentre study. Lancet. 2005; 366(9494): 1379-84[DOI]
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