Hepatitis Monthly

Published by: Kowsar

Non Alcoholic Fatty Liver Disease in Southern Iran: A Population Based Study

Kamran Bagheri Lankarani 1 , * , Fariborz Ghaffarpasand 1 , Mojtaba Mahmoodi 1 , Mehrzad Lotfi 2 , Nima Zamiri 1 , Sayed Taghi Heydari 3 , Mohammad Kazem Fallahzadeh 1 , Najmeh Maharlouei 1 , Meisam Babaeinejad 2 , Soheila Mehravar 4 and Bita Geramizadeh 5
Authors Information
1 Health Policy Research Centre, Shiraz University of Medical Sciences, Shiraz, IR Iran
2 Department of Radiology, Shiraz University of Medical Sciences, Shiraz, IR Iran
3 Department of Biostatistics, Jahrom University of Medical Sciences, Jahrom, IR Iran
4 Student Research Committee, Shiraz University of Medical Sciences, Shiraz, IR Iran
5 Department of Pathology, Transplant Research Centre, Shiraz University of Medical Sciences, Shiraz, IR Iran
Article information
  • Hepatitis Monthly: May 01, 2013, 13 (5); e9248
  • Published Online: May 23, 2013
  • Article Type: Research Article
  • Received: November 23, 2012
  • Accepted: March 10, 2013
  • DOI: 10.5812/hepatmon.9248

To Cite: Bagheri Lankarani K, Ghaffarpasand F, Mahmoodi M, Lotfi M, Zamiri N, et al. Non Alcoholic Fatty Liver Disease in Southern Iran: A Population Based Study, Hepat Mon. 2013 ; 13(5):e9248. doi: 10.5812/hepatmon.9248.

Copyright © 2013, Kowsar Corp. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
  • 1. Neuschwander-Tetri BA, Caldwell SH. Nonalcoholic steatohepatitis: summary of an AASLD Single Topic Conference. Hepatology. 2003; 37(5): 1202-19[DOI][PubMed]
  • 2. Vernon G, Baranova A, Younossi ZM. Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults. Aliment Pharmacol Ther. 2011; 34(3): 274-85[DOI][PubMed]
  • 3. Kojima S, Watanabe N, Numata M, Ogawa T, Matsuzaki S. Increase in the prevalence of fatty liver in Japan over the past 12 years: analysis of clinical background. J Gastroenterol. 2003; 38(10): 954-61[DOI][PubMed]
  • 4. Zhou YJ, Li YY, Nie YQ, Ma JX, Lu LG, Shi SL, et al. Prevalence of fatty liver disease and its risk factors in the population of South China. World J Gastroenterol. 2007; 13(47): 6419-24[PubMed]
  • 5. Crabb DW, Galli A, Fischer M, You M. Molecular mechanisms of alcoholic fatty liver: role of peroxisome proliferator-activated receptor alpha. Alcohol. 2004; 34(1): 35-8[DOI][PubMed]
  • 6. Machado M, Cortez-Pinto H. Non-alcoholic steatohepatitis and metabolic syndrome. Curr Opin Clin Nutr Metab Care. 2006; 9(5): 637-42[DOI][PubMed]
  • 7. Angelico F, Del Ben M, Conti R, Francioso S, Feole K, Maccioni D, et al. Non-alcoholic fatty liver syndrome: a hepatic consequence of common metabolic diseases. J Gastroenterol Hepatol. 2003; 18(5): 588-94[PubMed]
  • 8. Li H, Wang YJ, Tan K, Zeng L, Liu L, Liu FJ, et al. Prevalence and risk factors of fatty liver disease in Chengdu, Southwest China. Hepatobiliary Pancreat Dis Int. 2009; 8(4): 377-82[PubMed]
  • 9. Loria P, Lonardo A, Carulli L, Verrone AM, Ricchi M, Lombardini S, et al. Review article: the metabolic syndrome and non-alcoholic fatty liver disease. Aliment Pharmacol Ther. 2005; 22 Suppl 2: 31-6[DOI][PubMed]
  • 10. Targher G, Arcaro G. Non-alcoholic fatty liver disease and increased risk of cardiovascular disease. Atherosclerosis. 2007; 191(2): 235-40[DOI][PubMed]
  • 11. Manuck SB, Phillips JE, Gianaros PJ, Flory JD, Muldoon MF. Subjective socioeconomic status and presence of the metabolic syndrome in midlife community volunteers. Psychosom Med. 2010; 72(1): 35-45[DOI][PubMed]
  • 12. Santos AC, Ebrahim S, Barros H. Gender, socio-economic status and metabolic syndrome in middle-aged and old adults. BMC Public Health. 2008; 8: 62[DOI][PubMed]
  • 13. Alavian SM, Mohammad-Alizadeh AH, Esna-Ashari F, Ardalan G, Hajarizadeh B. Non-alcoholic fatty liver disease prevalence among school-aged children and adolescents in Iran and its association with biochemical and anthropometric measures. Liver Int. 2009; 29(2): 159-63[DOI][PubMed]
  • 14. Rogha M, Najafi N, Azari A, Kaji M, Pourmoghaddas Z, Rajabi F, et al. Non-alcoholic Steatohepatitis in a Sample of Iranian Adult Population: Age is a Risk Factor. Int J Prev Med. 2011; 2(1): 24-7[PubMed]
  • 15. Sohrabpour Amir Ali, Rezvan H, Amini-Kafiabad S, Dayhim MR, Merat Shahin, Pourshams Akram. Prevalence of nonalcoholic steatohepatitis in Iran: a population based study. Middle East J Dig Dis. 2011; 2(1): 14-19
  • 16. Merat Shahin, Yarahmadi S, Tahaghoghi S, Alizadeh Z, Sedighi N, Mansournia N, et al. Prevalence of Fatty Liver Disease among Type 2 Diabetes Mellitus Patients and its Relation to Insulin Resistance. Middle East J Dig Dis. 2011; 1(2): 74-79
  • 17. Anuurad E, Shiwaku K, Nogi A, Kitajima K, Enkhmaa B, Shimono K, et al. The new BMI criteria for asians by the regional office for the western pacific region of WHO are suitable for screening of overweight to prevent metabolic syndrome in elder Japanese workers. J Occup Health. 2003; 45(6): 335-43[PubMed]
  • 18. Shaw JE, de Courten M, Boyko EJ, Zimmet PZ. Impact of new diagnostic criteria for diabetes on different populations. Diabetes Care. 1999; 22(5): 762-6[PubMed]
  • 19. Saverymuttu SH, Joseph AE, Maxwell JD. Ultrasound scanning in the detection of hepatic fibrosis and steatosis. Br Med J (Clin Res Ed). 1986; 292(6512): 13-5[PubMed]
  • 20. Angulo P, Hui JM, Marchesini G, Bugianesi E, George J, Farrell GC, et al. The NAFLD fibrosis score: a noninvasive system that identifies liver fibrosis in patients with NAFLD. Hepatology. 2007; 45(4): 846-54[DOI][PubMed]
  • 21. Bellentani S, Bedogni G, Miglioli L, Tiribelli C. The epidemiology of fatty liver. Eur J Gastroenterol Hepatol. 2004; 16(11): 1087-93[PubMed]
  • 22. Omagari K, Kadokawa Y, Masuda J, Egawa I, Sawa T, Hazama H, et al. Fatty liver in non-alcoholic non-overweight Japanese adults: incidence and clinical characteristics. J Gastroenterol Hepatol. 2002; 17(10): 1098-105[PubMed]
  • 23. Park SH, Jeon WK, Kim SH, Kim HJ, Park DI, Cho YK, et al. Prevalence and risk factors of non-alcoholic fatty liver disease among Korean adults. J Gastroenterol Hepatol. 2006; 21(1 Pt 1): 138-43[DOI][PubMed]
  • 24. Kirovski G, Schacherer D, Wobser H, Huber H, Niessen C, Beer C, et al. Prevalence of ultrasound-diagnosed non-alcoholic fatty liver disease in a hospital cohort and its association with anthropometric, biochemical and sonographic characteristics. Int J Clin Exp Med. 2010; 3(3): 202-10[PubMed]
  • 25. Browning JD, Szczepaniak LS, Dobbins R, Nuremberg P, Horton JD, Cohen JC, et al. Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity. Hepatology. 2004; 40(6): 1387-95[DOI][PubMed]
  • 26. Bedogni G, Miglioli L, Masutti F, Tiribelli C, Marchesini G, Bellentani S. Prevalence of and risk factors for nonalcoholic fatty liver disease: the Dionysos nutrition and liver study. Hepatology. 2005; 42(1): 44-52[DOI][PubMed]
  • 27. Chen CH, Huang MH, Yang JC, Nien CK, Yang CC, Yeh YH, et al. Prevalence and risk factors of nonalcoholic fatty liver disease in an adult population of taiwan: metabolic significance of nonalcoholic fatty liver disease in nonobese adults. J Clin Gastroenterol. 2006; 40(8): 745-52[PubMed]
  • 28. De Lusong MA, Labio E, Daez L, Gloria V. Non-alcoholic fatty liver disease in the Philippines: comparable with other nations? World J Gastroenterol. 2008; 14(6): 913-7[PubMed]
  • 29. Rocha R, Cotrim HP, Bitencourt AG, Barbosa DB, Santos AS, Almeida Ade M, et al. Nonalcoholic fatty liver disease in asymptomatic Brazilian adolescents. World J Gastroenterol. 2009; 15(4): 473-7[PubMed]
  • 30. Fan JG, Zhu J, Li XJ, Chen L, Li L, Dai F, et al. Prevalence of and risk factors for fatty liver in a general population of Shanghai, China. J Hepatol. 2005; 43(3): 508-14[DOI][PubMed]
  • 31. Shen L, Fan JG, Shao Y, Zeng MD, Wang JR, Luo GH, et al. Prevalence of nonalcoholic fatty liver among administrative officers in Shanghai: an epidemiological survey. World J Gastroenterol. 2003; 9(5): 1106-10[PubMed]
  • 32. van der Poorten D, Milner KL, Hui J, Hodge A, Trenell MI, Kench JG, et al. Visceral fat: a key mediator of steatohepatitis in metabolic liver disease. Hepatology. 2008; 48(2): 449-57[DOI][PubMed]
  • 33. Lirussi F, Vitturi N, Azzalini L, Orando S, Orlando R, Plebani M, et al. Perihepatic adipose tissue thickness: a new non-invasive marker of NAFLD? J Gastrointestin Liver Dis. 2009; 18(1): 61-6[PubMed]
  • 34. Kim HJ, Lee KE, Kim DJ, Kim SK, Ahn CW, Lim SK, et al. Metabolic significance of nonalcoholic fatty liver disease in nonobese, nondiabetic adults. Arch Intern Med. 2004; 164(19): 2169-75[DOI][PubMed]
  • 35. Diehl AM, Goodman Z, Ishak KG. Alcohollike liver disease in nonalcoholics. A clinical and histologic comparison with alcohol-induced liver injury. Gastroenterology. 1988; 95(4): 1056-62[PubMed]
  • 36. Dassanayake AS, Kasturiratne A, Rajindrajith S, Kalubowila U, Chakrawarthi S, De Silva AP, et al. Prevalence and risk factors for non-alcoholic fatty liver disease among adults in an urban Sri Lankan population. J Gastroenterol Hepatol. 2009; 24(7): 1284-8[DOI][PubMed]
  • 37. Kelishadi R, Cook SR, Adibi A, Faghihimani Z, Ghatrehsamani S, Beihaghi A, et al. Association of the components of the metabolic syndrome with non-alcoholic fatty liver disease among normal-weight, overweight and obese children and adolescents. Diabetol Metab Syndr. 2009; 1: 29[DOI][PubMed]
  • 38. Okita M, Hayashi M, Sasagawa T, Takagi K, Suzuki K, Kinoyama S, et al. Effect of a moderately energy-restricted diet on obese patients with fatty liver. Nutrition. 2001; 17(7-8): 542-7[PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments