Hepatitis Monthly

Published by: Kowsar

Sexual Transmission of Hepatitis C Virus Between HIV Infected Subjects and Their Main Heterosexual Partners

Abbas Alipour 1 , * , Abbas Rezaianzadeh 2 , Jafar Hasanzadeh 2 , Abdorreza Rajaeefard 2 and Mohammad Ali Davarpanah 3
Authors Information
1 Community Medicine Department, School of Medicine, Mazandaran University of Medical Sciences, Sari, IR Iran
2 Epidemiology Department, School of Health and Nutrition, Research Center for Health Sciences, Shiraz University of Medical Sciences, Shiraz, IR Iran
3 HIV Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran
Article information
  • Hepatitis Monthly: November 01, 2013, 13 (11); e13593
  • Published Online: November 5, 2013
  • Article Type: Research Article
  • Received: July 14, 2013
  • Revised: September 19, 2013
  • Accepted: September 28, 2013
  • DOI: 10.5812/hepatmon.13593

To Cite: Alipour A, Rezaianzadeh A, Hasanzadeh J, Rajaeefard A, Davarpanah M A. Sexual Transmission of Hepatitis C Virus Between HIV Infected Subjects and Their Main Heterosexual Partners, Hepat Mon. 2013 ; 13(11):e13593. doi: 10.5812/hepatmon.13593.

Copyright © 2013, Kowsar Corp. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
  • 1. Ghany M, Strader D, Thomas D, Seeff L. Diagnosis,Management,and Treatment of HepatitisC: An Update. HEPATOLOGY. 2009; 49(4): 1335-1374
  • 2. Memon MI, Memon MA. Hepatitis C: an epidemiological review. J Viral Hepat. 2002; 9(2): 84-100[PubMed]
  • 3. Murphy EL, Bryzman SM, Glynn SA, Ameti DI, Thomson RA, Williams AE, et al. Risk factors for hepatitis C virus infection in United States blood donors. NHLBI Retrovirus Epidemiology Donor Study (REDS). HEPATOLOGY. 2000; 31(3): 756-62[PubMed]
  • 4. Tohme RA, Holmberg SD. is sexual contact a major mode of hepatitis C virus transmission? HEPATOLOGY. 2010; 52(4): 1497-1505
  • 5. Tortu S, McMahon JM, Pouget ER, Hamid R. Sharing of noninjection drug-use implements as a risk factor for hepatitis C. Subst Use Misuse. 2004; 39(2): 211-24[PubMed]
  • 6. Terrault NA. Sexual activity as a risk factor for hepatitis C. HEPATOLOGY. 2002; 36(5 Suppl 1)-105[PubMed]
  • 7. McMahon JM, Pouget ER, Tortu S. Individual and couple-level risk factors for hepatitis C infection among heterosexual drug users: a multilevel dyadic analysis. J Infect Dis. 2007; 195(11): 1572-81[PubMed]
  • 8. Thomas DL. Hepatitis C epidemiology. Curr Top Microbiol Immunol. 2000; 242: 25-41[PubMed]
  • 9. Alary M, Joly JR, Vincelette J, Lavoie R, Turmel B, Remis RS. Lack of evidence of sexual transmission of hepatitis C virus in a prospective cohort study of men who have sex with men. Am J Public Health. 2005; 95(3): 502-5[PubMed]
  • 10. Bollepalli S, Mathieson K, Jasiurkowski B, Hillier A, Post J, Bhanu S, et al. A comparison of risk factors for HCV-mono-infection, HIV-mono-infection, and HCV/HIV-co-infection in a community setting. Dig Dis Sci. 2008; 53(2): 517-21[PubMed]
  • 11. Fredrick T, Burian P, Terrault N, Cohen M, Augenbraun M, Young M, et al. factors associated with prevalent hepatitis C infection among HIV-infected women with no reported history of injection drug use: the womens interagency HIV study (WIHS) . Aids Patient Care STD. 2009; 23: 915-923
  • 12. Marincovich B, Castilla J, del Romero J, Garcia S, Hernando V, Raposo M, et al. Absence of hepatitis C virus transmission in a prospective cohort of heterosexual serodiscordant coupls. Sex Transm Infect. 2003; 79: 160-162
  • 13. Terrault NA, Dodge JL, Murphy EL, Tavis JE, Kiss A, Levin TR, et al. Sexual transmission of hepatitis C virus among monogamous heterosexual couples: the HCV partners study. HEPATOLOGY. 2013; 57(3): 881-9[DOI]
  • 14. Chen TY, Ding EL, Seage Iii GR, Kim AY. Meta-analysis: increased mortality associated with hepatitis C in HIV-infected persons is unrelated to HIV disease progression. Clin Infect Dis. 2009; 49(10): 1605-15[DOI][PubMed]
  • 15. Fan X, Mao Q, Zhou D, Lu Y, Xing J, Xu Y, et al. High diversity of hepatitis C viral quasispecies is associated with early virological response in patients undergoing antiviral therapy. HEPATOLOGY. 2009; 50(6): 1765-72[DOI][PubMed]
  • 16. Rezaianzadeh A, Hasanzadeh J, Alipour A, Davarpanah MA, Rajaeifard A, Tabatabaee SH. Impact of hepatitis C on survival of HIV-infected individuals in Shiraz; South of Iran. Hepat Mon. 2012; 12(2): 106-11[DOI]
  • 17. Thomas DL. Hepatitis C and human immunodeficiency virus infection. HEPATOLOGY. 2002; 36(5 Suppl 1)-9[DOI][PubMed]
  • 18. Ministry of Health . [Current statistics on HIV/AIDS infection in Islamic Republic of Iran]. 2011;
  • 19. Rahimi-Movaghar A, Amin-Esmaeili M, Haghdoost AA, Sadeghirad B, Mohraz M. HIV prevalence amongst injecting drug users in Iran: A systematic review of studies conducted during the decade 1998-2007. Int J Drug Policy. 2012; 23(4): 271-8[DOI][PubMed]
  • 20. Haghdoost A, Mostafavi E, Mirzazadeh A, Navadeh S, Feizzadeh A, Fahimfar N, et al. Modelling of HIV/AIDS in Iran up to 2014. Journal of AIDS and HIV Research. 2011; 3(12): 231-239
  • 21. Abu-Raddad LJ, Hilmi N, Mumtaz G, Benkirane M, Akala FA, Riedner G, et al. Epidemiology of HIV infection in the Middle East and North Africa. AIDS. 2010; 24 Suppl 2-23[DOI][PubMed]
  • 22. Twisk J. Applied Multilevel Analysis; A Practical Guide. 2010;
  • 23. Kenny D, Kashy D, Cook W. Dyadic Data Analysis. 2006;
  • 24. McMahon J, Pouget E, Tortu S. A guide for multilevel modelling of dyadic data with binary outcomes using SAS PROC NLMIXED. Comput Stat Data Anal. 2006; 50(12): 3663-3680
  • 25. Cook WL, Snyder DK. Analyzing nonindependent outcomes in couple therapy using the actor-partner interdependence model. J Fam Psychol. 2005; 19(1): 133-41[DOI][PubMed]
  • 26. Ludbrook J. Multiple comparison procedures updated. Clin Exp Pharmacol Physiol. 1998; 25(12): 1032-7
  • 27. Neuhaus JM. Analysis of clustered and longitudinal binary data subject to response misclassification. Biometrics. 2002; 58(3): 675-83
  • 28. Soriano V, Vispo E, Labarga P, Medrano J, Barreiro P. Viral hepatitis and HIV co-infection. Antiviral Res. 2010; 85(1): 303-15[DOI][PubMed]
  • 29. National AIDS Committee Ministry of Health. [Iran Country report on monitoring of the United Nations general assembly special session on HIV and AIDS, declaration of commitment]. 2008;
  • 30. Mohtasham Amiri Z, Rezvani M, Jafari Shakib R, Jafari Shakib A. Prevalence of hepatitis C virus infection and risk factors of drug using prisoners in Guilan province. Eastern Mediterranean health journal. 2007; 13(2): 250-256
  • 31. de Waure C, Cefalo C, Chiaradia G, Sferrazza A, Miele L, Gasbarrini G, et al. Intrafamilial transmission of hepatitis C virus in Italy: a systematic review. J Epidemiol Community Health. 2011; 64(10): 843-8[DOI][PubMed]
  • 32. Chkhartishvili N, McNutt LA, Smith PF, Tsertsvadze T. Characteristics of HIV-infected women and factors associated with HCV seropositivity in the Republic of Georgia. AIDS Res Ther. 2011; 8(1): 25[DOI][PubMed]
  • 33. Hajiani E, Masjedizadeh R, Hashemi J, Azmi M, Rajabi T. Hepatis C virus transmission and its risk factors within families of patients infected with hepatitis C virus in southern Iran: Khuzestan. World J Gastroenterol. 2006; 12(43): 7025-8[PubMed]
  • 34. Imani R, Habibian R, Karimi A, Nasiri J, Rahimian GA, Davarpanah M. Seroprevalence of Hepatitis C Virus in the Families of the Patients with Hepatitis C Infection in Shahre-Kord, Iran. Hepat Mon. 2010; 12: 472-475
  • 35. Ranjbar M, Golzardi Z, Sedigh L, Nekoozadeh S. Intrafamilial seropositivity of hepatitis in patients with hepatitis B and C virus in hepatitis clinic in Hamadan, Iran. Ann Hepatol. 2012; 11(1): 32-6
  • 36. Bollepalli S, Mathieson K, Bay C, Hillier A, Post J, Van Thiel DH, et al. Prevalence of risk factors for hepatitis C virus in HIV-infected and HIV/hepatitis C virus-coinfected patients. Sex Transm Dis. 2007; 34(6): 367-70[PubMed]
  • 37. Ghosn J, Deveau C, Goujard C, Garrigue I, Saichi N, Galimand J, et al. Increase in hepatitis C virus incidence in HIV-1-infected patients followed up since primary infection. Sex Transm Infect. 2006; 82(6): 458-60[PubMed]
  • 38. Stroffolini T, Lorenzoni U, Menniti-Ippolito F, Infantolino D, Chiaramonte M. Hepatitis C virus infection in spouses: sexual transmission or common exposure to the same risk factors? Am J Gastroenterol. 2001; 96(11): 3138-41[PubMed]
  • 39. Wolff FH, Fuchs SC, Barcellos NT, Falavigna M, Cohen M, Brandão ABM, et al. Risk factors for hepatitis C virus infection in individuals infected with the HIV. Digestive and Liver Disease. 2008; 40(6): 460-467
  • 40. Ackerman Z, Ackerman E, Paltiel O. Intrafamilial transmission of hepatitis C virus: a systematic review. J Viral Hepat. 2000; 7(2): 93-103[PubMed]
  • 41. Fassio E, Landeira G, Longo C, Dominguez N, Alvarez E, Gualano G. Risk factors for infection in chronic hepatitis C: a high prevalence of sexual exposure among human immunodeficiency virus-coinfected women. HEPATOLOGY. 2011; 54(1): 379[DOI]
  • 42. Halfon P, Riflet H, Renou C, Quentin Y, Cacoub P. Molecular evidence of male-to-female sexual transmission of hepatitis C virus after vaginal and anal Intercourse. J Clin Microbiol. 2001; 39: 1204-1206
  • 43. Luksamijarulkul P, Piroonamornpun P, Triamchaisri SK. Hepatitis B seromarkers, hepatitis C antibody, and risk behaviors in married couples, a bordered province of western Thailand: Hepatitis B seromarkers, hepatitis C antibody, and risk behaviors. Hepat Mon. 2012; 11(4): 273-7
  • 44. Nyamathi A, Robbins W, Fahey J, Wiley D, Pekler V, Longshore D, et al. Prevalence and predictors of hepatitis C virus RNA in the semen of homeless men. Biol Res Nurs. 2002; 4: 22-30
  • 45. Perz JF, Grytdal S, Beck S, Fireteanu AM, Poissant T, Rizzo E, et al. Case-control study of hepatitis B and hepatitis C in older adults: Do healthcare exposures contribute to burden of new infections? HEPATOLOGY. 2012; [DOI]
  • 46. Danta M, Rodger AJ. Transmission of HCV in HIV-positive populations. Curr Opin HIV AIDS. 2011; 6(6): 451-8[DOI][PubMed]
  • 47. Danta M, Dusheiko GM. Acute HCV in HIV-positive individuals - a review. Curr Pharm Des. 2008; 14(17): 1690-7[PubMed]
  • 48. Lackner AA, Mohan M, Veazey RS. The gastrointestinal tract and AIDS pathogenesis. Gastroenterology. 2009; 136(6): 1965-78[PubMed]
  • 49. Thomson EC, Fleming VM, Main J, Klenerman P, Weber J, Eliahoo J, et al. Predicting spontaneous clearance of acute hepatitis C virus in a large cohort of HIV-1-infected men. Gut. 2010; 60(6): 837-45[DOI]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments