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Hepatitis C Virus Infection in Iran; Viral Spread Routes in General Population and Safety Measures

AUTHORS

Muhammad Sohail Afzal 1 , * , Tahir Ahmad 2 , Haroon Ahmed 3

AUTHORS INFORMATION

1 Department of Chemistry, School of Science, University of Management and Technology (UMT), Lahore, Pakistan

2 Atta ur Rahman School of Applied Biosciences, National University of Science and Technology, Islamabad, Pakistan

3 Department of Biosciences, COMSATS Institute of Information Technology, Islamabad, Pakistan

ARTICLE INFORMATION

Hepatitis Monthly: 15 (10); e17343
Published Online: October 24, 2015
Article Type: Letter
Received: January 2, 2014
Accepted: January 4, 2014
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Keywords

Prevalence Awareness HCV General Population Viral Spread Roots

Copyright © 2015, Kowsar Corp. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

Dear Editor,

Hepatitis C virus (HCV) is the leading cause of liver related morbidity and mortality in the world; with more than 180 million infected patients (1). HCV prevalence is very low in Iran. The recent reports from Iran showed that HCV prevalence in general population was about 0.05% - 0.2% (2, 3). Due to globalization and traveling worldwide, especially to the neighboring countries, there is a chance of viral spread (4). The major factors involved in HCV spread are intravenous drug abuse, unhealthy medical practices, sharing contaminated objects such as needles and barbers' unawareness (5). Host factors are also involved in disease susceptibility, progression and viral self-clearance (6, 7). Recently, Zamani et al. (3) showed that unsterile punctures and history of infection in family members were associated with HCV spread. Despite obligatory blood screening for HCV, the prevalence of HCV infection raised dramatically in recent decades in the Middle-Eastern region. Currently, HCV prevalence in general Iranian population is very low; massive awareness campaigns should be done on a regular basis to educate general population to control the viral spread.

Footnotes
References
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  • 2. Shakeri MT, Nomani H, Ghayour Mobarhan M, Sima HR, Gerayli S, Shahbazi S, et al. The prevalence of hepatitis C virus in mashhad, iran: a population-based study. Hepat Mon. 2013; 13(3)[DOI][PubMed]
  • 3. Zamani F, Sohrabi M, Poustchi H, Keyvani H, Saeedian FS, Ajdarkosh H, et al. Prevalence and Risk Factors of Hepatitis C Virus Infection in Amol City, North of Iran: A Population-Based Study (2008-2011). Hepat Mon. 2013; 13(12)[DOI][PubMed]
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  • 6. Afzal MS, Tahir S, Salman A, Baig TA, Shafi T, Zaidi NU, et al. Analysis of interleukin-10 gene polymorphisms and hepatitis C susceptibility in Pakistan. J Infect Dev Ctries. 2011; 5(6) : 473 -9 [PubMed]
  • 7. Afzal MS, Anjum S, Zaidi NUSS. Effect of Functional Interleukin-10 Polymorphism on Pegylated Interferon-α Plus Ribavirin Therapy Response in Chronic Hepatitis C Virus Patients Infected With 3a Genotype in Pakistani Population. Hepat Mon. 2013; 13(6)[DOI][PubMed]
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