Hepatitis Monthly

Published by: Kowsar

HBV Vaccination Status and Response to Hepatitis B Vaccine Among Iranian Dentists, Correlation With Risk Factors and Preventive Measures

Nafiseh Momeni 1 , Mohammad Sadegh Ahmad Akhoundi 1 , 2 , Seyed Moayed Alavian 3 , Ahmad Reza Shamshiri 4 , Mehdy Norouzi 5 , Nima Mahboobi 1 , Nilufar Moosavi 1 and Seyed Mohammad Jazayeri 5 , *
Authors Information
1 Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, IR Iran
2 Orthodontic Department, Faculty of Dentistry, Tehran University of Medical Sciences, Tehran, IR Iran
3 Middle East Liver Diseases Center (MELD Centers), Tehran, IR Iran
4 Research Center for Caries Prevention, Dentistry Research Institute, Department of Community Oral Health, Tehran University of Medical Sciences, Tehran, IR Iran
5 Hepatitis B Molecular Laboratory, Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, IR Iran
Article information
  • Hepatitis Monthly: January 01, 2015, 15 (1); e20014
  • Published Online: December 27, 2014
  • Article Type: Research Article
  • Received: May 5, 2014
  • Accepted: December 6, 2014
  • DOI: 10.5812/hepatmon.20014

To Cite: Momeni N, Ahmad Akhoundi M S, Alavian S M, Shamshiri A R, Norouzi M, et al. HBV Vaccination Status and Response to Hepatitis B Vaccine Among Iranian Dentists, Correlation With Risk Factors and Preventive Measures, Hepat Mon. 2015 ; 15(1):e20014. doi: 10.5812/hepatmon.20014.

Copyright © 2014, Kowsar Corp. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Materials and Methods
4. Results
5. Discussion
  • 1. Shah SM, Merchant AT, Dosman JA. Percutaneous injuries among dental professionals in Washington State. BMC Public Health. 2006; 6: 269[DOI][PubMed]
  • 2. Vadivale M, Tan TC, Ong CN. Sero-prevalence of hepatitis B infection among dental professionals. Singapore Med J. 1992; 33(4): 367-9[PubMed]
  • 3. Song KB, Choi KS, Lang WP, Jacobson JJ. Hepatitis B prevalence and infection control among dental health care workers in a community in South Korea. J Public Health Dent. 1999; 59(1): 39-43[PubMed]
  • 4. Reingold AL, Kane MA, Hightower AW. Failure of gloves and other protective devices to prevent transmission of hepatitis B virus to oral surgeons. JAMA. 1988; 259(17): 2558-60[PubMed]
  • 5. Thomas DL, Gruninger SE, Siew C, Joy ED, Quinn TC. Occupational risk of hepatitis C infections among general dentists and oral surgeons in North America. Am J Med. 1996; 100(1): 41-5[PubMed]
  • 6. Mahboobi N, Agha-Hosseini F, Safari S, Lavanchy D, Alavian SM. Hepatitis B virus infection in dentistry: a forgotten topic. J Viral Hepat. 2010; 17(5): 307-16[DOI][PubMed]
  • 7. Hofmann F, Kralj N. Criteria for successful hepatitis B vaccination in adults: results of a case study. Infection. 2009; 37(3): 266-9[DOI][PubMed]
  • 8. Ammon A, Reichart PA, Pauli G, Petersen LR. Hepatitis B and C among Berlin dental personnel: incidence, risk factors, and effectiveness of barrier prevention measures. Epidemiol Infect. 2000; 125(2): 407-13[PubMed]
  • 9. Batista SM, Andreasi MS, Borges AM, Lindenberg AS, Silva AL, Fernandes TD, et al. Seropositivity for hepatitis B virus, vaccination coverage, and vaccine response in dentists from Campo Grande, Mato Grosso do Sul, Brazil. Mem Inst Oswaldo Cruz. 2006; 101(3): 263-7[PubMed]
  • 10. Cleveland JL, Siew C, Lockwood SA, Gruninger SE, Gooch BF, Shapiro CN. Hepatitis B vaccination and infection among U.S. dentists, 1983-1992. J Am Dent Assoc. 1996; 127(9): 1385-90[PubMed]
  • 11. Alavian SM, Akbari H, Ahmadzad-Asl M, Kazem M, Davoudi A, Tavangar H. Concerns regarding dentists' compliance in hepatitis B vaccination and infection control. Am J Infect Control. 2005; 33(7): 428-9[DOI][PubMed]
  • 12. Alavian SM, Mahboobi N. Anti-HBs antibody status and some of its associated factors in dental health care workers in Tehran University of Medical Sciences: Anti-HBs Ab and associated factors in dental society. Hepat Mon. 2011; 11(2): 99-102[PubMed]
  • 13. Alavian SM, Mahboobi N, Savadrudbari MM, Azar PS, Daneshvar S. Iranian dental students' knowledge of hepatitis B virus infection and its control practices. J Dent Educ. 2011; 75(12): 1627-34[PubMed]
  • 14. Alavian SM, Izadi M, Zare AA, Lankarani MM, Assari S, Vardi MM. Survey of the level of anti-HBs antibody titer in vaccinated Iranian general dentists. Spec Care Dentist. 2008; 28(6): 265-70[DOI][PubMed]
  • 15. McMahon BJ, Bruden DL, Petersen KM, Bulkow LR, Parkinson AJ, Nainan O, et al. Antibody levels and protection after hepatitis B vaccination: results of a 15-year follow-up. Ann Intern Med. 2005; 142(5): 333-41[PubMed]
  • 16. Desombere I, Hauser P, Rossau R, Paradijs J, Leroux-Roels G. Nonresponders to hepatitis B vaccine can present envelope particles to T lymphocytes. J Immunol. 1995; 154(2): 520-9[PubMed]
  • 17. Bialek SR, Bower WA, Novak R, Helgenberger L, Auerbach SB, Williams IT, et al. Persistence of protection against hepatitis B virus infection among adolescents vaccinated with recombinant hepatitis B vaccine beginning at birth: a 15-year follow-up study. Pediatr Infect Dis J. 2008; 27(10): 881-5[DOI][PubMed]
  • 18. Valats JC, Tuaillon E, Funakoshi N, Hoa D, Brabet MC, Bollore K, et al. Investigation of memory B cell responses to hepatitis B surface antigen in health care workers considered as non-responders to vaccination. Vaccine. 2010; 28(39): 6411-6[DOI][PubMed]
  • 19. Williams JL, Christensen CJ, McMahon BJ, Bulkow LR, Cagle HH, Mayers JS, et al. Evaluation of the response to a booster dose of hepatitis B vaccine in previously immunized healthcare workers. Vaccine. 2001; 19(28-29): 4081-5[PubMed]
  • 20. Milich DR, Leroux-Roels GG. Immunogenetics of the response to HBsAg vaccination. Autoimmun Rev. 2003; 2(5): 248-57[PubMed]
  • 21. Hohler T, Stradmann-Bellinghausen B, Starke R, Sanger R, Victor A, Rittner C, et al. C4A deficiency and nonresponse to hepatitis B vaccination. J Hepatol. 2002; 37(3): 387-92[PubMed]
  • 22. Chen W, Gluud C. Vaccines for preventing hepatitis B in health-care workers. Cochrane Database Syst Rev. 2005; (4)[DOI][PubMed]
  • 23. Alimonos K, Nafziger AN, Murray J, Bertino JS, Jr.. Prediction of response to hepatitis B vaccine in health care workers: whose titers of antibody to hepatitis B surface antigen should be determined after a three-dose series, and what are the implications in terms of cost-effectiveness? Clin Infect Dis. 1998; 26(3): 566-71[PubMed]
  • 24. Sjogren MH. Prevention of hepatitis B in nonresponders to initial hepatitis B virus vaccination. Am J Med. 2005; 118 Suppl 10A: 34S-9S[DOI][PubMed]
  • 25. Zuckerman JN, Sabin C, Craig FM, Williams A, Zuckerman AJ. Immune response to a new hepatitis B vaccine in healthcare workers who had not responded to standard vaccine: randomised double blind dose-response study. BMJ. 1997; 314(7077): 329-33[PubMed]
  • 26. Averhoff F, Mahoney F, Coleman P, Schatz G, Hurwitz E, Margolis H. Immunogenicity of hepatitis B Vaccines. Implications for persons at occupational risk of hepatitis B virus infection. Am J Prev Med. 1998; 15(1): 1-8[PubMed]
  • 27. Propst T, Propst A, Lhotta K, Vogel W, Konig P. Reinforced intradermal hepatitis B vaccination in hemodialysis patients is superior in antibody response to intramuscular or subcutaneous vaccination. Am J Kidney Dis. 1998; 32(6): 1041-5[PubMed]
  • 28. Raz R, Koren R, Bass D. Safety and immunogenicity of a new mammalian cell-derived recombinant hepatitis B vaccine containing Pre-S1 and Pre-S2 antigens in adults. Isr Med Assoc J. 2001; 3(5): 328-32[PubMed]
  • 29. Yap I, Guan R, Chan SH. Recombinant DNA hepatitis B vaccine containing Pre-S components of the HBV coat protein--a preliminary study on immunogenicity. Vaccine. 1992; 10(7): 439-42[PubMed]
  • 30. John M. Hepatitis B immunization and postimmunization serology. J Can Dent Assoc. 2000; 66(10): 551-2[PubMed]
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