Hepatitis Monthly

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Genotype 4 Hepatitis E Virus Prevalent in Eastern China Shows Diverse Subtypes

Hua Tian 1 , Xingli Fu 2 , Wang Li 2 , Yuan Huang 2 , Jiayao Sun 2 , Gai Zhou 2 , Chengli Zhou 2 , Quan Shen 2 , Shixing Yang 2 and Wen Zhang 2 , *
Authors Information
1 Jiangsu Provincial Center for Disease Prevention and Control, Nanjing, China
2 Department of Microbiology, School of Medicine, Jiangsu University, Zhenjiang, China
Article information
  • Hepatitis Monthly: June 2015, 15 (6); e25367
  • Published Online: June 23, 2015
  • Article Type: Brief Report
  • Received: November 15, 2014
  • Revised: April 18, 2015
  • Accepted: June 6, 2015
  • DOI: 10.5812/hepatmon.25367v2

To Cite: Tian H, Fu X, Li W, Huang Y, Sun J, et al. Genotype 4 Hepatitis E Virus Prevalent in Eastern China Shows Diverse Subtypes, Hepat Mon. 2015 ;15(6):e25367. doi: 10.5812/hepatmon.25367v2.

Copyright: Copyright © 2015, Hepatitis Monthly. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited..
1. Background
2. Objectives
3. Materials and Methods
4. Results
5. Discussion
  • 1. Kamar N, Selves J, Mansuy JM, Ouezzani L, Peron JM, Guitard J, et al. Hepatitis E virus and chronic hepatitis in organ-transplant recipients. N Engl J Med. 2008; 358(8): 811-7[DOI][PubMed]
  • 2. Meng XJ, Purcell RH, Halbur PG, Lehman JR, Webb DM, Tsareva TS, et al. A novel virus in swine is closely related to the human hepatitis E virus. Proc Natl Acad Sci U S A. 1997; 94(18): 9860-5[PubMed]
  • 3. Zhang W, Shen Q, Mou J, Gong G, Yang Z, Cui L, et al. Hepatitis E virus infection among domestic animals in eastern China. Zoonoses Public Health. 2008; 55(6): 291-8[PubMed]
  • 4. Zhou C, Li W, Yang S. Analysis of hepatitis e virus-like sequence in chimpanzee. Hepat Mon. 2014; 14(9)[DOI][PubMed]
  • 5. Han J, Zeng H, Wang L, Liu P, Liu L, Xia J, et al. Hepatitis E virus infection in farmed rabbits and swine in the Eastern Chinese city Lianyungang: showing no potential interspecies transmission. J Med Virol. 2014; 86(11): 1898-904[DOI][PubMed]
  • 6. Widen F, Ayral F, Artois M, Olofson AS, Lin J. PCR detection and analysis of potentially zoonotic Hepatitis E virus in French rats. Virol J. 2014; 11: 90[DOI][PubMed]
  • 7. Song YJ, Park WJ, Park BJ, Lee JB, Park SY, Song CS, et al. Hepatitis E virus infections in humans and animals. Clin Exp Vaccine Res. 2014; 3(1): 29-36[DOI][PubMed]
  • 8. Holla RP, Ahmad I, Ahmad Z, Jameel S. Molecular virology of hepatitis E virus. Semin Liver Dis. 2013; 33(1): 3-14[DOI][PubMed]
  • 9. Zhang W, He Y, Wang H, Shen Q, Cui L, Wang X, et al. Hepatitis E virus genotype diversity in eastern China. Emerg Infect Dis. 2010; 16(10): 1630-2[DOI][PubMed]
  • 10. Dai X, Dong C, Zhou Z, Liang J, Dong M, Yang Y, et al. Hepatitis E virus genotype 4, Nanjing, China, 2001-2011. Emerg Infect Dis. 2013; 19(9): 1528-30[DOI][PubMed]
  • 11. Lu L, Li C, Hagedorn CH. Phylogenetic analysis of global hepatitis E virus sequences: genetic diversity, subtypes and zoonosis. Rev Med Virol. 2006; 16(1): 5-36[DOI][PubMed]
  • 12. Zhang W, Shen Q, Mou J, Yang ZB, Yuan CL, Cui L, et al. Cross-species infection of hepatitis E virus in a zoo-like location, including birds. Epidemiol Infect. 2008; 136(8): 1020-6[PubMed]
  • 13. Zheng Y, Ge S, Zhang J, Guo Q, Ng MH, Wang F, et al. Swine as a principal reservoir of hepatitis E virus that infects humans in eastern China. J Infect Dis. 2006; 193(12): 1643-9[DOI][PubMed]
  • 14. Wang H, He Y, Shen Q, Wang X, Yang S, Cui L, et al. Complete genome sequence of the genotype 4 hepatitis E virus strain prevalent in swine in Jiangsu Province, China, reveals a close relationship with that from the human population in this area. J Virol. 2012; 86(15): 8334-5[DOI][PubMed]
  • 15. Huang FF, Haqshenas G, Guenette DK, Halbur PG, Schommer SK, Pierson FW, et al. Detection by reverse transcription-PCR and genetic characterization of field isolates of swine hepatitis E virus from pigs in different geographic regions of the United States. J Clin Microbiol. 2002; 40(4): 1326-32[PubMed]
  • 16. Wibawa ID, Suryadarma IG, Tsuda F, Matsumoto Y, Ninomiya M, et al. Identification of genotype 4 hepatitis E virus strains from a patient with acute hepatitis E and farm pigs in Bali, Indonesia. J Med Virol. 2007; 79(8): 1138-46[DOI][PubMed]
  • 17. Yan Y, Zhang W, Shen Q, Cui L, Hua X. Prevalence of four different subgenotypes of genotype 4 hepatitis E virus among swine in the Shanghai area of China. Acta Vet Scand. 2008; 50: 12[DOI][PubMed]
  • 18. Zhang W, Yang S, Ren L, Shen Q, Cui L, Fan K, et al. Hepatitis E virus infection in central China reveals no evidence of cross-species transmission between human and swine in this area. PLoS One. 2009; 4(12)[DOI][PubMed]
  • 19. Geng Y, Zhao C, Fan J, Harrison TJ, Zhang H, Lian H, et al. Genotype analysis of hepatitis E virus from sporadic hepatitis E cases in northern China. Infect Genet Evol. 2013; 20: 413-7[DOI][PubMed]
  • 20. Zhang W, Yang S, Shen Q, Huang F, Shan T, Yang Z, et al. Genotype 3 hepatitis E virus existed among swine groups in 4 geographically far regions in China. Vet Microbiol. 2010; 140(1-2): 193-5[DOI][PubMed]
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