Acute Fatty Liver of Pregnancy: A Life-Threatening Condition Requiring a Life-Saving Approach

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To Cite : Gorginzadeh M, Safari S, Alavian S M. Acute Fatty Liver of Pregnancy: A Life-Threatening Condition Requiring a Life-Saving Approach, Hepat Mon. 2016 ;16(6):e35256. doi: 10.5812/hepatmon.35256.
Copyright: Copyright © 2016, Hepatitis Monthly. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited..
  • 1. Engelmann G, Hoffmann GF, Grulich-Henn J, Teufel U. Alanine aminotransferase elevation in obese infants and children: a marker of early onset non alcoholic Fatty liver disease. Hepat Mon. 2014; 14(4): 14112[DOI][PubMed]
  • 2. Bugianesi E, McCullough AJ, Marchesini G. Insulin resistance: a metabolic pathway to chronic liver disease. Hepatology. 2005; 42(5): 987-1000[DOI][PubMed]
  • 3. Xiong HF, Liu JY, Guo LM, Li XW. Acute fatty liver of pregnancy: over six months follow-up study of twenty-five patients. World J Gastroenterol. 2015; 21(6): 1927-31[DOI][PubMed]
  • 4. Vigil-de Gracia P, Montufar-Rueda C. Acute fatty liver of pregnancy: diagnosis, treatment, and outcome based on 35 consecutive cases. J Matern Fetal Neonatal Med. 2011; 24(9): 1143-6[DOI][PubMed]
  • 5. Riely CA. Liver disease in the pregnant patient. . Am J Gastroenterol. 1999; 94(7): 1728-32[DOI][PubMed]
  • 6. Shah JM, Mehta MN, Viradiya HB. Acute fatty liver of pregnancy. IJCP. 2013; 23(9): 550-2
  • 7. Kamimura K, Abe H, Kawai H, Kamimura H, Kobayashi Y, Nomoto M, et al. Advances in understanding and treating liver diseases during pregnancy: A review. World J Gastroenterol. 2015; 21(17): 5183-90[DOI][PubMed]
  • 8. Goel A, Jamwal KD, Ramachandran A, Balasubramanian KA, Eapen CE. Pregnancy-related liver disorders. J Clin Exp Hepatol. 2014; 4(2): 151-62[DOI][PubMed]
  • 9. Kobayashi T, Minami S, Mitani A, Tanizaki Y, Booka M, Okutani T, et al. Acute fatty liver of pregnancy associated with fetal mitochondrial trifunctional protein deficiency. J Obstet Gynaecol Res. 2015; 41(5): 799-802[DOI][PubMed]
  • 10. Cowie P, Johnston IG. Acute Fatty Liver of Pregnancy. 2010; : 1-5
  • 11. Ko H, Yoshida EM. Acute fatty liver of pregnancy. Can J Gastroenterol. 2006; 20(1): 25-30[PubMed]
  • 12. Zhu T, Li Q, Zhang W, Huang J, Peng Q, Liu Y, et al. Screening time and schedule for outpatients with acute fatty liver of pregnancy. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2015; 40(7): 748-53[PubMed]
  • 13. Mohammad Jafari R, Saadati N, Rezaie M. Acute Fatty Liver of Pregnancy: A Clinical-Paraclinical Survey. JJHR. 2015; 6(1)[DOI]
  • 14. Meng J, Wang S, Gu Y, Lv H, Jiang J, Wang X. Prenatal predictors in postpartum recovery for acute fatty liver of pregnancy: experiences at a tertiary referral center. Arch Gynecol Obstet. 2016; 293(6): 1185-91[DOI][PubMed]
  • 15. Association of Anaesthetists of Great Britain and Ireland , Thomas D, Wee M, Clyburn P, Walker I, et al. Blood transfusion and the anaesthetist: management of massive haemorrhage. Anaesthesia. 2010; 65(11): 1153-61[PubMed]
  • 16. Stainsby D, Jones H, Asher D, Atterbury C, Boncinelli A, Brant L, et al. Serious hazards of transfusion: a decade of hemovigilance in the UK. Transfus Med Rev. 2006; 20(4): 273-82[DOI][PubMed]
  • 17. Crochemore T, de Toledo Piza FM, Silva E, Correa TD. Thromboelastometry-guided hemostatic therapy: an efficacious approach to manage bleeding risk in acute fatty liver of pregnancy: a case report. J Med Case Rep. 2015; 9(1): 202[DOI][PubMed]
  • 18. K S, Thunga S, Narayanan A, Singh P. Recombinant activated factor VII in the management of acute fatty liver of pregnancy: A case report. J Obstet Gynaecol Res. 2015; 41(7): 1122-5[DOI][PubMed]
  • 19. Ding J, Han LP, Lou XP, Geng LN, Liu D, Yang Q, et al. Effectiveness of combining plasma exchange with plasma perfusion in acute fatty liver of pregnancy: a retrospective analysis. Gynecol Obstet Invest. 2015; 79(2): 97-100[DOI][PubMed]
  • 20. Arya S, Richardson CJ, Jain S, Swischuck LE. Early Vitamin K Deficiency Bleeding in a Neonate Associated with Maternal Acute Fatty Liver of Pregnancy. AJP Rep. 2015; 5(2): 193-5[DOI][PubMed]
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