Prevalence of Serologic Hepatitis B Markers in Blood Donors From Puebla, Mexico: The Association of Relatively High Levels of Anti-Core Antibodies With the Detection of Surface Antigen and Genomic DNA

Authors Information
Article Notes and Dates
To Cite : Sosa-Jurado F, Hilda Rosas-Murrieta N, Guzman-Flores B, Perez Zempoaltecalt C, Patricia Sanchez Torres A, et al. Prevalence of Serologic Hepatitis B Markers in Blood Donors From Puebla, Mexico: The Association of Relatively High Levels of Anti-Core Antibodies With the Detection of Surface Antigen and Genomic DNA, Hepat Mon. 2016 ;16(6):e36942. doi: 10.5812/hepatmon.36942.
Copyright: Copyright © 2016, Hepatitis Monthly. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited..
Abstract
1. Background
2. Objectives
3. Materials and Methods
4. Results
5. Discussion
Acknowledgements
Footnotes
References
  • 1. Elgouhari HM, Abu-Rajab Tamimi TI, Carey WD. Hepatitis B virus infection: understanding its epidemiology, course, and diagnosis. Cleve Clin J Med. 2008; 75(12): 881-9[DOI][PubMed]
  • 2. de la Fuente RA, Gutierrez ML, Garcia-Samaniego J, Fernandez-Rodriguez C, Lledo JL, Castellano G. Pathogenesis of occult chronic hepatitis B virus infection. World J Gastroenterol. 2011; 17(12): 1543-8[DOI][PubMed]
  • 3. Larrubia JR. Occult hepatitis B virus infection: a complex entity with relevant clinical implications. World J Gastroenterol. 2011; 17(12): 1529-30[DOI][PubMed]
  • 4. Valdespino JL, Conde-González CJ, Olaiz-Fernández G, Palma O, Sepúlveda J. Prevalencia en México de la infección y el estado de portador de la hepatitis B en adultos. Salud Pública de México. 2007; 49-11[DOI]
  • 5. Roman S, Tanaka Y, Khan A, Kurbanov F, Kato H, Mizokami M, et al. Occult hepatitis B in the genotype H-infected Nahuas and Huichol native Mexican population. J Med Virol. 2010; 82(9): 1527-36[DOI][PubMed]
  • 6. Garcia-Montalvo BM, Farfan-Ale JA, Acosta-Viana KY, Puerto-Manzano FI. Hepatitis B virus DNA in blood donors with anti-HBc as a possible indicator of active hepatitis B virus infection in Yucatan, Mexico. Transfus Med. 2005; 15(5): 371-8[DOI][PubMed]
  • 7. Garcia-Montalvo BM, Ventura-Zapata LP. Molecular and serological characterization of occult hepatitis B infection in blood donors from Mexico. Ann Hepatol. 2011; 10(2): 133-41[PubMed]
  • 8. Gish RG, Lau JY, Brooks L, Fang JW, Steady SL, Imperial JC, et al. Ganciclovir treatment of hepatitis B virus infection in liver transplant recipients. Hepatology. 1996; 23(1): 1-7[DOI][PubMed]
  • 9. Saitou N, Nei M. The neighbor-joining method: a new method for reconstructing phylogenetic trees. Mol Biol Evol. 1987; 4(4): 406-25[PubMed]
  • 10. Tamura K, Peterson D, Peterson N, Stecher G, Nei M, Kumar S. MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol Biol Evol. 2011; 28(10): 2731-9[DOI][PubMed]
  • 11. Lazarevic I. Clinical implications of hepatitis B virus mutations: recent advances. World J Gastroenterol. 2014; 20(24): 7653-64[DOI][PubMed]
  • 12. Huang CH, Yuan Q, Chen PJ, Zhang YL, Chen CR, Zheng QB, et al. Influence of mutations in hepatitis B virus surface protein on viral antigenicity and phenotype in occult HBV strains from blood donors. J Hepatol. 2012; 57(4): 720-9[DOI][PubMed]
  • 13. ARCHITECT HBsAg Qualitative, REF 1P97, 48-582/R2, B1P970. Technical manual. 2009;
  • 14. La'ulu SL, Roberts WL. The analytic sensitivity and mutant detection capability of six hepatitis B surface antigen assays. Am J Clin Pathol. 2006; 125(5): 748-51[DOI][PubMed]
  • 15. Chiquete E, Sanchez LV, Becerra G, Quintero A, Maldonado M, Panduro A. Performance of the serologic and molecular screening of blood donations for the hepatitis B and C viruses in a Mexican Transfusion Center. Ann Hepatol. 2005; 4(4): 275-8[PubMed]
  • 16. Monteon VM, Reyes-Lopez PA, Sosa-Palacio A, Leon-Tello G, Martinez-Murguia J, Sosa-Jurado F. [Heterogeneous distribution of the prevalence of anti-Trypanosoma cruzi antibodies among blood donors in the State of Puebla, Mexico]. Salud Publica Mex. 2005; 47(2): 116-25[PubMed]
  • 17. Garcia-Montalvo BM. [Seropositivity of HIV, HBV, HCV and Treponema pallidum in blood donors in southeast Mexico]. Rev Invest Clin. 2006; 58(6): 567-72[PubMed]
  • 18. Rojas-Garcia Mde J, Aguilar-Tlapale R, Montalvo-Melo MC, Sanchez- Aleman MA, Hernandez-Giron C. [Seroprevalence of sexually transmitted infections in blood donors from the state blood transfusion center, Tlaxcala, Mexico]. Salud Publica Mex. 2008; 50(6): 437-8[PubMed]
  • 19. Valerio-Urena J, Vasquez-Fernandez F, Perez-Sosa JA, Cortazar-Benitez LF, Chavez-Tapia NC, Ruvalcaba-Rojas OA, et al. [Prevalence of VHB and VHC serological markers among blood donors in the capital state of Veracruz, Mexico]. Gac Med Mex. 2009; 145(3): 183-7[PubMed]
  • 20. Serrano Machuca JJ, Villarreal Rios E, Galicia Rodriguez L, Vargas Daza ER, Martinez Gonzalez L, Mejia Damian AF. [Detection of antibodies present in blood donors in Mexico]. Rev Panam Salud Publica. 2009; 26(4): 355-9[PubMed]
  • 21. Juarez-Figueroa LA, Uribe-Salas FJ, Conde-Gonzalez CJ. Heterogeneous distribution of hepatitis B serological markers in rural areas of Mexico. Salud Publica Mex. 2011; 53 Suppl 1-31[PubMed]
  • 22. Seo DH, Whang DH, Song EY, Han KS. Occult hepatitis B virus infection and blood transfusion. World J Hepatol. 2015; 7(3): 600-6[DOI][PubMed]
  • 23. Brechot C, Thiers V, Kremsdorf D, Nalpas B, Pol S, Paterlini-Brechot P. Persistent hepatitis B virus infection in subjects without hepatitis B surface antigen: clinically significant or purely "occult"? Hepatology. 2001; 34(1): 194-203[DOI][PubMed]
  • 24. Mulrooney-Cousins PM, Michalak TI. Persistent occult hepatitis B virus infection: experimental findings and clinical implications. World J Gastroenterol. 2007; 13(43): 5682-6[PubMed]
  • 25. Samal J, Kandpal M, Vivekanandan P. Molecular mechanisms underlying occult hepatitis B virus infection. Clin Microbiol Rev. 2012; 25(1): 142-63[DOI][PubMed]
  • 26. Gerlich WH. Diagnostic problems caused by HBsAg mutants-a consensus report of an expert meeting. Intervirology. 2004; 47(6): 310-3[PubMed]
  • 27. Yoshikawa A, Gotanda Y, Minegishi K, Taira R, Hino S, Tadokoro K, et al. Lengths of hepatitis B viremia and antigenemia in blood donors: preliminary evidence of occult (hepatitis B surface antigen-negative) infection in the acute stage. Transfusion. 2007; 47(7): 1162-71[DOI][PubMed]
  • 28. O'Brien SF, Fearon MA, Yi QL, Fan W, Scalia V, Muntz IR, et al. Hepatitis B virus DNA-positive, hepatitis B surface antigen-negative blood donations intercepted by anti-hepatitis B core antigen testing: the Canadian Blood Services experience. Transfusion. 2007; 47(10): 1809-15[DOI][PubMed]
  • 29. Said ZN, Sayed MH, Salama ,I, Aboel-Magd EK, Mahmoud MH, Setouhy ME, et al. Occult hepatitis B virus infection among Egyptian blood donors. World J Hepatol. 2013; 5(2): 64-73[DOI][PubMed]
  • 30. Allain JP, Cox L. Challenges in hepatitis B detection among blood donors. Curr Opin Hematol. 2011; 18(6): 461-6[DOI][PubMed]
  • 31. Stramer SL, Zou S, Notari EP, Foster GA, Krysztof DE, Musavi F, et al. Blood donation screening for hepatitis B virus markers in the era of nucleic acid testing: are all tests of value? Transfusion. 2012; 52(2): 440-6[DOI][PubMed]
  • 32. Kiely P, Margaritis AR, Seed CR, Yang H, Australian Red Cross Blood Service NG. Hepatitis B virus nucleic acid amplification testing of Australian blood donors highlights the complexity of confirming occult hepatitis B virus infection. Transfusion. 2014; 54(8): 2084-91[DOI][PubMed]
  • 33. Alvarado-Esquivel C, Sablon E, Conde-Gonzalez CJ, Juarez-Figueroa L, Ruiz-Maya L, Aguilar-Benavides S. Molecular analysis of hepatitis B virus isolates in Mexico: predominant circulation of hepatitis B virus genotype H. World J Gastroenterol. 2006; 12(40): 6540-5[PubMed]
  • 34. Ruiz-Tachiquin ME, Valdez-Salazar HA, Juarez-Barreto V, Dehesa-Violante M, Torres J, Munoz-Hernandez O, et al. Molecular analysis of hepatitis B virus "a" determinant in asymptomatic and symptomatic Mexican carriers. Virol J. 2007; 4: 6[DOI][PubMed]
  • 35. Roman S, Panduro A, Aguilar-Gutierrez Y, Maldonado M, Vazquez-Vandyck M, Martinez-Lopez E, et al. A low steady HBsAg seroprevalence is associated with a low incidence of HBV-related liver cirrhosis and hepatocellular carcinoma in Mexico: a systematic review. Hepatol Int. 2009; 3(2): 343-55[DOI][PubMed]
  • 36. Cruz JR, Perez-Rosales MD. Availability, safety, and quality of blood for transfusion in the Americas. Rev Panam Salud Publica. 2003; 13(2-3): 103-10[PubMed]
  • 37. General health information management, Epidemiological and Statistical deaths Subsystem (SEED). General deaths (INEGI / HEALTH). 2015;
  • 38. Zhang M, Wu R, Jiang J, Minuk GY, Niu J. The presence of hepatitis B core antibody is associated with more advanced liver disease in alcoholic patients with cirrhosis. Alcohol. 2013; 47(7): 553-8[DOI][PubMed]
  • 39. Xie M, Rao W, Yang T, Deng Y, Zheng H, Pan C, et al. Occult hepatitis B virus infection predicts de novo hepatitis B infection in patients with alcoholic cirrhosis after liver transplantation. Liver Int. 2015; 35(3): 897-904[DOI][PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:

Author(s):

Article(s):

Create Citiaion Alert via Google Reader

Cited By:

Hepatitis Monthly accepts terms & conditions of:

International Committee of Medical Journal Editors (ICMJE) Citedby Linking DOI enabled Crossref iThenticate COPE Cross Check