Hepatitis Monthly

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Hepatocellular Carcinoma and Its Precursors in 103 HBV-Related Cirrhotic Explanted Livers: A Study from South Iran

Shahrzad Yazdanpanah 1 , Bita Geramizadeh 1 , 2 , * , Saman Nikeghbalian 2 , 3 and Seyed Ali Malek-Hosseini 2 , 3
Authors Information
1 Department of Pathology, Shiraz University of Medical Sciences, Shiraz, IR Iran
2 Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran
3 Department of Surgery, Hepatobiliary and Liver Transplant Section, Shiraz University of Medical Sciences, Shiraz, IR Iran
Article information
  • Hepatitis Monthly: August 01, 2016, 16 (8); e38584
  • Published Online: July 20, 2016
  • Article Type: Research Article
  • Received: April 27, 2016
  • Revised: June 18, 2016
  • Accepted: June 28, 2016
  • DOI: 10.5812/hepatmon.38584

To Cite: Yazdanpanah S, Geramizadeh B, Nikeghbalian S, Malek-Hosseini S A. Hepatocellular Carcinoma and Its Precursors in 103 HBV-Related Cirrhotic Explanted Livers: A Study from South Iran, Hepat Mon. 2016 ;16(8):e38584. doi: 10.5812/hepatmon.38584.

Abstract
Copyright © 2016, Kowsar Corp. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
Footnote
References
  • 1. Geramizadeh B, Nikeghbalian S, Kazemi K, Shamsaifar A, Bahador A, Salahi H, et al. Hepatocellular carcinoma in explanted livers of patients with genotype d HBV cirrhosis: report of the first experience from Iran. Arch Iran Med. 2013; 16(6): 348-50[PubMed]
  • 2. Kim do Y, Han KH. Epidemiology and surveillance of hepatocellular carcinoma. Liver Cancer. 2012; 1(1): 2-14[DOI][PubMed]
  • 3. Kim SR, Ikawa H, Ando K, Mita K, Fuki S, Sakamoto M, et al. Multistep hepatocarcinogenesis from a dysplastic nodule to well-differentiated hepatocellular carcinoma in a patient with alcohol-related liver cirrhosis. World J Gastroenterol. 2007; 13(8): 1271-4[PubMed]
  • 4. Park YN. Update on precursor and early lesions of hepatocellular carcinomas. Arch Pathol Lab Med. 2011; 135(6): 704-15[DOI][PubMed]
  • 5. Shokouhi S, Rakhshan M, Gachkar L, Khalaj E, Sazgar S. Effects of Hepatitis B Surface and Hepatitis B Core Antigens from Hepatitis B Virus Genotypes B and C on In Vitro Apoptosis. Hep Mon. 2007; 7: 217-21
  • 6. Constantinescu I, Dinu AA, Boscaiu V, Niculescu M. Hepatitis B virus core promoter mutations in patients with chronic hepatitis B and hepatocellular carcinoma in bucharest, romania. Hepat Mon. 2014; 14(10)[DOI][PubMed]
  • 7. Jia W, Qi X, Ji YY, Xun YH, Wang H, Zhang WH, et al. Low Serum Hepatitis B Surface Antigen Level Predicts Compensated Cirrhosis Caused by Chronic Hepatitis B in HBeAg Positive Patients in East China. Hepat Mon. 2015; 15(8)[DOI][PubMed]
  • 8. International Consensus Group for Hepatocellular NeoplasiaThe International Consensus Group for Hepatocellular N. Pathologic diagnosis of early hepatocellular carcinoma: a report of the international consensus group for hepatocellular neoplasia. Hepatology. 2009; 49(2): 658-64[DOI][PubMed]
  • 9. Kojiro M, Roskams T. Early hepatocellular carcinoma and dysplastic nodules. Semin Liver Dis. 2005; 25(2): 133-42[DOI][PubMed]
  • 10. Kondo F. Histological features of early hepatocellular carcinomas and their developmental process: for daily practical clinical application : Hepatocellular carcinoma. Hepatol Int. 2009; 3(1): 283-93[DOI][PubMed]
  • 11. Hytiroglou P. Morphological changes of early human hepatocarcinogenesis. Semin Liver Dis. 2004; 24(1): 65-75[DOI][PubMed]
  • 12. Mohammadi Z, Keshtkar A, Eghtesad S, Jeddian A, Pourfatholah AA, Maghsudlu M, et al. Epidemiological Profile of Hepatitis B Virus Infection in Iran in the Past 25 years; A Systematic Review and Meta-analysis of General Population Studies. Middle East J Dig Dis. 2016; 8(1): 5-18[DOI][PubMed]
  • 13. Lee RG, Tsamandas AC, Demetris AJ. Large cell change (liver cell dysplasia) and hepatocellular carcinoma in cirrhosis: matched case-control study, pathological analysis, and pathogenetic hypothesis. Hepatology. 1997; 26(6): 1415-22[DOI][PubMed]
  • 14. Niu ZS, Niu XJ, Wang WH, Zhao J. Latest developments in precancerous lesions of hepatocellular carcinoma. World J Gastroenterol. 2016; 22(12): 3305-14[DOI][PubMed]
  • 15. Koo JS, Seong JK, Park C, Yu DY, Oh BK, Oh SH, et al. Large liver cell dysplasia in hepatitis B virus x transgenic mouse liver and human chronic hepatitis B virus-infected liver. Intervirology. 2005; 48(1): 16-22[DOI][PubMed]
  • 16. Watanabe S, Okita K, Harada T, Kodama T, Numa Y, Takemoto T, et al. Morphologic studies of the liver cell dysplasia. Cancer. 1983; 51(12): 2197-205[PubMed]
  • 17. Plentz RR, Park YN, Lechel A, Kim H, Nellessen F, Langkopf BH, et al. Telomere shortening and inactivation of cell cycle checkpoints characterize human hepatocarcinogenesis. Hepatology. 2007; 45(4): 968-76[DOI][PubMed]
  • 18. El-Sayed SS, El-Sadany M, Tabll AA, Soltan A, El-Dosoky I, Attallah AM. DNA ploidy and liver cell dysplasia in liver biopsies from patients with liver cirrhosis. Can J Gastroenterol. 2004; 18(2): 87-91[PubMed]
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