Hepatitis C in Pakistan: A Review of Available Data


Muhammad Umar 1 , * , Hamama tul Bushra 2 , Masood Ahmad 2 , Muhammad Khurram 2 , Saima Usman 2 , Mohammad Arif 2 , Tashfeen Adam 2 , Zahid Minhas 2 , Adnan Arif 2 , Abdul Naeem 2 , Khushnud Ejaz 2 , Zameer Butt 2 , Muhammad Bilal 2

1 Rawalpindi Medical College, [email protected], Pakistan

2 Department of Medicine, Rawalpindi Medical College, Holy Family Hospital, Pakistan

How to Cite: Umar M, Bushra H, Ahmad M, Khurram M, Usman S, et al. Hepatitis C in Pakistan: A Review of Available Data, Hepat Mon. Online ahead of Print ; 10(3):205-214.


Hepatitis Monthly: 10 (3); 205-214
Article Type: Review Article
Received: July 16, 2009
Accepted: March 3, 2010





Hepatitis C virus (HCV) infection is increasingly recognized as a major health care problem, and is found frequently in Pakistani settings. In this article we reviewed published and unpublished data related to the seroepidemiology of HCV infection in Pakistan. For this article, data from 132 published studies and three unpublished data sets published/ presented between the period 1992-2008 were utilized. Data of 1,183,329 individuals were gathered. Blood donors (982,481) and the general population (178,322) constituted the majority of these subjects. The frequency of HCV infection in blood donors and in the general population was 3.0 % (95% CI: 3.0- 3.1) and 4.7 (95% CI: 4.6 -4.8), respectively. The frequency among 6,148 pregnant females was 7.3% (95% CI = 6.7 – 8.0). The frequency in healthy children ranged from 0.4 to 4.1% (95% CI = 1.4 – 2.3). Pakistani HCV serofrequency figures are significantly higher (P < 0.0001) compared to those of the corresponding populations in surrounding countries like India, Nepal, Myanmar, Iran and Afghanistan.


Hepatitis C Virus Anti-HCV Pakistan Serofrequency

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