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Source and Response of Antibody to Hepatitis B Vaccine in Hemodialysis Patients

AUTHORS

Zohreh Aminzadeh 1 , * , Hossein Akhavan 2 , Latif Gachkar 3

1 Associate Professor of Infectious Diseases,Shaheed Beheshti University of Medical Sciences, zohrehaminzadeh@yahoo.com, Tehran, IR.IRAN

2 Infectious Diseases Specialist, Tehran, IR.IRAN

3 Tehran, IR.IRAN

How to Cite: Aminzadeh Z, Akhavan H, Gachkar L. Source and Response of Antibody to Hepatitis B Vaccine in Hemodialysis Patients, Hepat Mon. Online ahead of Print ; 7(1):33-34.

ARTICLE INFORMATION

Hepatitis Monthly: 7 (1); 33-34
Article Type: Brief Report
Received: March 23, 2006
Accepted: October 21, 2006

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Abstract

Background and Aims: All chronic hemodialysis patients for hepatitis B infection have to be tested and vaccinated against HBV infection routinely.

Methods: A descriptive study was designed in 47 hemodialysis patients. After a blood sample was taken for serologic status, three doses (0, 1, 6 month) of hepatitis B vaccine were administered. Repeated titers were obtained one month after the last vaccination and analyzed by ELISA.

Results: 39 patients (83%) became immune with protective levels of HBs antibody. There was not a significant correlation between sex, age, smoking, underlying diseases, weight, duration of dialysis and positive HBs antibody after vaccination.

Conclusions: Hmodialysis patients need follow-up testing.

Keywords

Hemodialysis Hepatitis B Vaccination

© 0, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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