IF: 1.578
Cite Score:
1.45
THOMSON REUTERS - SCOPUS

Evaluation of the Level of HBV Antibody Titer after HBV Vaccination among Children in Tehran, Iran

AUTHORS

Seyed Mohammad Javad Hosseini 1 , * , Reza Ranjbar 2 , Hassan Abolghasemi 2 , Mohammad Turkaman 2

AUTHORS INFORMATION

1 Molecular Biology Research Center, Baqiyatallah University of Medical Sciences, ranjbar@bmsu.ac.ir, IR-Iran

2 Molecular Biology Research Center, Baqiyatallah University of Medical Sciences, IR-Iran

How to Cite: Hosseini S, Ranjbar R, Abolghasemi H, Turkaman M. Evaluation of the Level of HBV Antibody Titer after HBV Vaccination among Children in Tehran, Iran, Hepat Mon. Online ahead of Print ; 9(2):150-153.

ARTICLE INFORMATION

Hepatitis Monthly: 9 (2); 150-153
Article Type: Brief Report
Received: August 21, 2008
Accepted: January 27, 2009

Crossmark

CHEKING

READ FULL TEXT
Abstract

Background and Aims: Hepatitis B infection is a serious public health problem worldwide. It has been shown that the levels of antibody to hepatitis B surface antigen (anti-HBs) decrease after vaccination. The main objective of this study was to assess the level of anti-HBs among children after primary vaccination against hepatitis B virus (HBV) in Tehran, Iran.

Methods: The study was conducted in four selected healthcare centers in Tehran during a 6-month period from September 2005 to March 2006 in Tehran. Blood samples collected from 165 healthy, 1- to 5-year-old children who had been vaccinated against HBV were tested for anti-HBs using enzyme-linked immunosorbent assay (ELISA).

Results: Approximately 47.9 % of the cases were male. Among the cases, the minimum and maximum titers of hepatitis B surface antibodies (HBsAb) were zero and 1000 m IU, respectively. The mean level of HBsAb titer in this study was 232.64 m IU, with a standard deviation of 278.711 m IU.

Conclusions: The results showed that HBsAb titer may decrease over time after vaccination. Finally, along with prevention and control strategies, ongoing investigation and monitoring of antibody levels against HBV in children and other age ranges is recommended.

Keywords

HBV Antibody Vaccination Children Iran

© 0, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

Full Text

Full text is available in PDF

COMMENTS

LEAVE A COMMENT HERE: