Seroprevalence of hepatitis B virus among hemodialysis patients in Bushehr province, southern Iran
Hepatitis Monthly: 11 (3); 200-202 Article Type: Research Article
October 12, 2010
November 9, 2010
D. et al. Seroprevalence of hepatitis B virus among hemodialysis patients in Bushehr province, southern Iran,
Online ahead of Print
Background: Hepatitis B virus (HBV) infection is still reported from adult hemodialysis units. Objectives: To determine the prevalence of anti-HBs antibody in hemodialysis patients and the correlation between levels of anti-HBs antibody with other factors. Patients and Methods: HBsAg, anti-HBs and anti-HBc antibodies level in 119 hemodialysis patients were evaluated by enzyme-linked immunosorbent assay. Results: Seroconversion (anti-HBs antibody >10 IU/L) was found in 22 patients. Minimum protective antibody level was found in patients aged ≥60 years. Statistically significant correlation was not found between anti-HBs antibody and gender. Ten (8.4%) patients had abnormal ALT and/or AST. Prevalence of HBsAg, anti-HBc antibody, HBeAg and anti-HBe antibody were found in 8 (6.72%), 24 (25.16%), 2 (1.68%) and 3 (2.52%) patients, respectively. Conclusions: Periodic assessment of anti-HBs antibody level is strongly recommended in patients undergoing hemodialysis.
Implication for health policy/practice/research/medical education: Hepatitis B virus infection, as one of the major infections, can be seen in hemodialysis patients more than normal population. Knowledge and attitude against HBV in this patients should be considered by health policy maker and medical trainers.
Please cite this paper as: Mostaghni AA, Soltanian A, Mokhtari E, Japoni S, Mehrabani D. Seroprevalence of hepatitis B virus among hemodialysis patients in Bushehr province, southern Iran. Hepat Mon. 2011;11(3):200-202.
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