Factors Correlated With Hepatitis C and B Virus Infections Among Injecting Drug Users in Tehran, IR Iran

AUTHORS

Masoumeh Amin-Esmaeili 1 , Masoumeh Amin-Esmaeili 1 , Afarin Rahimi-Movaghar 1 , * , Afarin Rahimi-Movaghar 2 , * , Emran M. Razaghi 1 , Emran M. Razaghi 2 , Ahmad Reza Baghestani 1 , Ahmad Reza Baghestani 3 , Siavash Jafari 3 , Siavash Jafari 4

1 Iranian Research Center for HIV/AIDS, Tehran University of Medical Sciences, Tehran, IR Iran

2 Psychiatry Department, Tehran University of Medical Sciences, Tehran, IR Iran

3 Islamic Azad University, South Tehran Branch, Tehran, IR Iran

4 Faculty of Medicine, School of Population and Public Health, The University of British Columbia, Vancouver, Canada

Corresponding Authors:

How to Cite: Amin-Esmaeili M, Amin-Esmaeili M, Rahimi-Movaghar A, Rahimi-Movaghar A, Razaghi E, et al. Factors Correlated With Hepatitis C and B Virus Infections Among Injecting Drug Users in Tehran, IR Iran, Hepat Mon. Online ahead of Print ; 12(1):23-31. doi: 10.5812/kowsar.1735143X.806.

ARTICLE INFORMATION

Hepatitis Monthly: 12 (1); 23-31
Published Online: December 31, 2011
Article Type: Research Article
Received: October 8, 2011
Accepted: January 2, 2012
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Abstract

Background: In Iran, the number of injecting drug users (IDUs) has increased in recent years. The rates of hepatitis C virus (HCV) and hepatitis B virus (HBV) infections among IDUs are reportedly high.

Objectives: The purpose of this study was to assess factors correlated with HCV and HBV infections among IDUs in Tehran.

Patients and Methods: A cross-sectional study included 899 IDUs recruited from the community, drug treatment centers, and drop-in-centers. The study involved interviews conducted using an adapted version of the WHO Drug Injection Study Phase II (Version 2b) questionnaire and blood testing for the HCV antibody, hepatitis B surface antigen, and hepatitis B core antibody. A logistic regression model was used to identify independent factors correlated with HCV and HBV infections.

Results: HCV infection was found to be primarily associated with female gender [odds ratio (OR) 5.0, 95% confidence interval (CI) 2.0-10.0)], unmarried status (OR 2.9, 95% CI 1.9-4.4), drug use for more than 10 years (OR 2.7, 95% CI 1.8-3.9), drug injection frequency of more than once per day (OR 2.6, 95% CI 1.6-4.2), history of imprisonment (OR 2.5, 95% CI 1.6-4.0)], and a history of shared injection needles in prison (OR 2.3, 95% CI 1.5-3.6). HBV infection was mainly correlated with a history of imprisonment (OR 1.9, 95% CI 1.4-2.7) and drug use for more than 10 years (OR 1.4, 95% CI 1.1-1.9).

Conclusions: Because a considerable number of IDUs in Iran are receiving reduction services, tailoring services for prevention of hepatitis infection are necessary.

Keywords

Hepatitis Viruses Prevalence Risk Factors Risk Behavior Iran

© 2011, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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