IF: 1.578
Cite Score:

The Effect of Education on Quality of Life in Patients under Interferon Therapy


Ahmad Ali Asadi Noghabi 1 , * , Mitra Zandi 2 , Abbas Mehran 2 , Seyed Moayed Alavian 2 , Ali Hasanpour Dehkordi 3


1 School of Midwifery and Nursing, Tehran University of Medical Sciences, asadin@tums.ac.ir, IR-Iran

2 School of Medical Sciences, Tarbiat Modares University, IR-Iran

3 Faculty of Medicine, Shahrekord University of Medical Sciences, IR-Iran

How to Cite: Noghabi A A, Zandi M, Mehran A, Alavian S, Dehkordi A. The Effect of Education on Quality of Life in Patients under Interferon Therapy, Hepat Mon. Online ahead of Print ; 10(3):218-222.


Hepatitis Monthly: 10 (3); 218-222
Article Type: Brief Report
Received: March 18, 2009
Accepted: December 24, 2009




Background and Aims: The main purpose of treating and caring for patients with chronic viral hepatitis is to promote life satisfaction and a feeling of well-being in patients suffering from this disease. The aim of this study was to evaluate the effect of education on quality of life in patients with chronic hepatitis who were treated with Interferon alpha.

Methods: This quasi-experimental study was conducted on 60 patients with viral hepatitis. The intervention included teaching them the method of self injection of Interferon alpha 2 b, giving them educational pamphlets and then following their continuing treatment with interferon. Patients were randomly assigned to two 30-patient groups. The data- gathering tool was a demographic characteristics questionnaire and the Quality of Life Questionnaire for Patients with Chronic Liver Disease (CLDQ). The educational program was done in four 45- minute sessions for the case group and their relatives. The follow-up period was 12 weeks. Quality of life in patients with chronic hepatitis was measured before initiating interferon therapy, and after the educational period. Quality of life in the two groups was compared.

Results: The total quality of life score in the two groups before therapy did not show any significant difference (P = 0.351); while 12 weeks after education there was a significant difference between the two groups (P < 0.001) in three items including abdominal symptoms (P = 0.01), worry (P < 0.001) and emotional factors (P < 0.001). The other three items did not show a significant difference between the two groups. The total quality of life score in the case group was significantly different before and after education (P < 0.001), and improved after education. The total quality of life score in the control group did not differ significantly after 12 weeks (P = 0.143).

Conclusions: Planning short and simple educational programs has a significant effect on the patient’s control of his/her disease and its side effects; and can improve quality of life, life satisfaction, and mechanisms of coping with treatment in patients with viral hepatitis.


Education Viral Hepatitis Quality of Life Interferon Therapy

© 0, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

Full Text

Full text is available in PDF