IF: 1.578
Cite Score:

Seroprevalence Study of Hepatitis C and Hepatitis B Virus among Hospitalized Intravenous Drug Users in Ahvaz, Iran (2002-2006)


Seyed Mohammad Alavi 1 , * , Fatemeh Behdad 2

1 Infectious and Tropical Disease Research Center, Ahvaz Jundishapur University of Medical Sciences, alavil329dr@yahoo.com, Khoozestan, IR.Iran

2 Infectious Disease Division, Razi Hospital, Ahvaz Jundishapur University of Medical Sciences, Khoozestan, IR.Iran

How to Cite: Alavi S, Behdad F. Seroprevalence Study of Hepatitis C and Hepatitis B Virus among Hospitalized Intravenous Drug Users in Ahvaz, Iran (2002-2006), Hepat Mon. Online ahead of Print ; 10(2):101-104.


Hepatitis Monthly: 10 (2); 101-104
Article Type: Research Article
Received: December 3, 2009
Accepted: March 18, 2010




Background and Aims: Viral hepatitis is a serious complication among intravenous drug users (IDUs). The objectives of this study were to determine the seroprevalence of hepatitis B and C viruses (HBV and HCV), and associated risk factors among IDUs at a teaching hospital in Ahvaz, southwest Iran.

Methods: Medical records of 333 IDUs hospitalized from 2002 to 2006 at Razi Hospital, which is affiliated to Ahvaz Jundishapur University of Medical Sciences, were reviewed. Cases meeting the criteria for a diagnosis of viral hepatitis infection were included in this study. Patients’ characteristics, clinical and laboratory findings were extracted. Data of cases with hepatitis virus infection (HIV), called the HIV group and without HIV, called the NHIV group, were compared, using the chi-square test for qualitative variables and the t-test for quantitative variables. Differences with a P < 0.05 were considered significant.

Results: Out of a total of 333 IDUs, 115 (34.5%), mostly male, with a mean age of 24.8±6.2 had HIV. More than 65% had a history of imprisonment. The mean duration of IDU was 4.5±1.6 years for the HIV group and 1.8±0.4 years for the NHIV group (P < 0.05). 85% of the HIV group and 45% of the NHIV group shared injection equipment (P < 0.05). 103 patients (30.9%) had HCV and 12 (3.6%) had HBV infection. There was a significant difference in age, duration of drug abuse, time spent in prison, sharing injection equipment, history of surgery, blood transfusion, packs of cigarettes per year and human immunodeficiency virus (HIV) co-infection between the two groups (P < 0.05).

Conclusions: HIV in IDU population is a prevalent complication, and is associated with heavy smoking (high number of packs of cigarettes per year), sharing injection equipment, long duration of drug usage, long duration of prison stay, HIV co-infection, history of surgery, blood and blood products transfusion. Older age, longer duration of IDU and imprisonment put the cases at higher risk of acquiring HCV in comparison to HBV.


Intravenous Drug Users Viral Hepatitis HBV HCV

© 0, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

Full Text

Full text is available in PDF