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Seroprevalence of Hepatitis Viruses B, C, D and HIV Infection Among Hemodialysis Patients in Kerman Province, South-East Iran

AUTHORS

Mohammad Javad Zahedi 1 , Sodaif Darvish Moghaddam 2 , * , Seyed Moayed Alavian 3 , Mahdieh Dalili 1

AUTHORS INFORMATION

1 Department of Internal Medicine, Physiology Research Center, Kerman University of Medical Sciences, IR Iran

2 Department of Internal Medicine, Physiology Research Center, Kerman University of Medical Sciences, sdmoghadam@kmu.ac.ir, IR Iran

3 Baqiyatallah Research Center for Gastroenterology and Liver diseases, Baqiyatallah University of Medical Sciences, IR Iran

How to Cite: Zahedi M, Darvish Moghaddam S, Alavian S, Dalili M. Seroprevalence of Hepatitis Viruses B, C, D and HIV Infection Among Hemodialysis Patients in Kerman Province, South-East Iran, Hepat Mon. Online ahead of Print ; 12(5):339-343. doi: 10.5812/hepatmon.5969.

ARTICLE INFORMATION

Hepatitis Monthly: 12 (5); 339-343
Article Type: Research Article
Received: April 1, 2012
Accepted: April 25, 2012
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Abstract

Background: The prevalence of hepatitis viruses in hemodialysis patients has been reported to be much greater than in the general population. Attention to local data, effectively guides health planners so that they can control infections and prevent nosocomial transmissions.
Objectives: This cross sectional study was carried out to determine the prevalence of hepatitis B (HBV), hepatitis C (HCV), and hepatitis D (HDV) viruses, as well as the human immunode?ciency virus (HIV) in dialysis centers in the Kerman Province, in the southeast of Iran.
Patients and Methods: All hemodialysis patients (n = 228) in 7 centers were enrolled in the study. Hepatitis B surface antigens (HBsAg), HCV antibodies (Ab), HDV Ab and HIV Ab were measured using speci?c enzyme linked immunoassay kits (ULTRA kit, bioMérieux, France) and con?rmed by a qualitative PCR assay.
Results: The studied group was comprised of 92 (40.4%) females and 136 (59.6%) males. The mean age of the patients was 51 ± 9.5 years and the duration of hemodialysis was 39.7 ± 7.9 months. Positive HBsAg was found in 7% of cases, HCV Ab in 7%, and patients with both viruses were detected in 1.7% cases. HIV Ab and HDV Ab were negative in all cases. Out of the other risk factors, frequency of blood transfusions was signi?cantly correlated with positive HCV Ab (P < 0.008).
Conclusions: Prevalence of HBV and HCV in hemodialysis patients was moderate to low in the Kerman Province, as in other parts of the country. Strict adherence to protective measures could lead to even lower rates.


Implication for health policy/practice/research/medical education:
In order to reduce the prevalence of viral hepatitis in hemodialysis centers, more adherence to protective measures are highly recommended.
Please cite this paper as:
Zahedi MJ, Darvish Moghadam S, Alavian SM, Dalili M. Seroprevalence of Hepatitis B, C, D and HIV Infection Among Hemodialysis Patients in Kerman Province, South-East Iran. Hepat Mon. 2012;12(5):339-42. DOI: 10.5812/hepatmon.5969

Copyright © 2012 Kowsar Corp. All rights reserved.


Keywords

Hepatitis B Virus Hepatitis C Virus Hepatitis Delta Virus Hemodialysis

© 0, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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